About Us:

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Position Summary:

The Clinical Trial Finance Manager will support the financial planning, tracking, and analysis of clinical trial activities across Structure Therapeutics’ development programs. Reporting to the Senior Director, Clinical Trial Finance, this role will serve as a key partner to Clinical Operations, Project Management, and Accounting, ensuring timely and accurate financial reporting, accruals, and vendor oversight.

This position offers an exciting opportunity to contribute to the growth of a global, publicly traded biotech company and play a hands-on role in supporting the execution of our clinical programs.

Job Responsibilities:

• Support and manage budgeting, forecasting, and financial planning processes for clinical trials, ensuring alignment with corporate and program objectives.
• Partner with Clinical Operations, Project Management and FP&A to track clinical study spend, perform variance analyses, and assess key cost drivers.
• Prepare and maintain clinical trial accruals; ensure timely, accurate expense recognition in accordance with GAAP and company’s accounting policies.
• Assist in reviewing and maintaining clinical trial contracts, work orders, and amendments to ensure financial accuracy and compliance with agreed terms.
• Support month-end and quarter-end close activities, including variance analysis, journal entries, and account reconciliations related to clinical trial costs.
• Maintain financial models and dashboards to track trial performance and support decision-making.
• Collaborate with Accounting Operations and FP&A to ensure proper coding, forecasting, and reporting of clinical spend.
• Provide financial insights and ad hoc analyses to cross-functional stakeholders.
• Contribute to the continuous improvement of financial processes, systems, and internal controls related to clinical operations.
• Assist with internal and external audits, including preparation of audit schedules and SOX documentation as needed.

Qualifications:

Education

• Bachelor’s degree in finance, Accounting, or related field required.
• CPA or MBA preferred.

Experience

• Minimum 5-8 years of relevant finance experience, with at least 3 years in biotech or pharmaceutical clinical trial finance.
• Strong understanding of clinical development processes, CRO/vendor management, and accrual methodologies.
• Experience supporting multi-site or global clinical trials preferred.
• Excellent analytical, problem-solving, and communication skills.
• Ability to work cross-functionally in a dynamic, fast-paced environment.
• Advanced Microsoft Excel skills are a must.
• Experience with NetSuite, Zip and Condor are a plus.

Preferred Experience

• Prior experience in a publicly traded biotech or pharmaceutical company.
• Familiarity with financial compliance requirements (SOX, GAAP).
• Strong attention to detail and ability to manage multiple priorities.

Travel Required:

Occasional travel may be required based on business needs.

Structure Therapeutics Inc. is an Equal-Opportunity Employer.

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $112,000-$138,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.

At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees.

We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.

Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.

Fraud Alert

To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at BambooHR.

Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.