Job Title: Manager/Sr. Manager, China Clinical Project & Vendor Operations

Reports To: Director, Clinical Operations, APAC Region

Location: Shanghai, China

About Us:

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Position Summary:

The role establishes, maintains, and operates the company’s clinical outsourcing procurement and vendor governance framework while acting as an operational partner to China clinical project delivery. The incumbent collaborates with Clinical Operations/PM, Legal, Finance, and external service providers to ensure outsourced clinical activities are delivered on time, on budget, and in compliance with GCP, local regulations, and internal standards. This position integrates procurement discipline, vendor performance management, and clinical project management support to drive study execution quality and efficiency.

Job Responsibilities:

• Clinical Project Management Support & Vendor Oversight
  • Support Clinical Operations/PM during study planning to define vendor scope, cost estimates, timelines, and resourcing.
  • Lead vendor identification and selection based on study needs, historic performance, and risk assessment.
  • Track vendor deliverables, milestones, KPIs, and quality; facilitate timely escalation, RCA, and CAPA.
  • Coordinate the review and approval of Change Orders (COs), assessing impacts on budget, timeline, and risk.
  • Provide data‑driven comparisons and recommendations for operational decision‑making.

• Procurement Process Development & Compliance
  • Build and optimize China clinical procurement SOPs and work instructions aligned with GCP and local requirements.
  • Co‑manage MSA/SOW templates with Legal/Regulatory for key categories (site CTA, CRO, SMO, Central Labs, Imaging, eCOA, RTSM, EDC, etc.).
  • Maintain the Approved Vendor List (AVL) and implement qualification, evaluation, and performance feedback mechanisms.
  • Ensure audit/inspection readiness and adherence to internal controls.

• Contracting & Business Operations
  • Lead RFI/RFP processes: preparation, issuance, vendor Q&A, proposal collection, and comparative analysis.
  • Coordinate full contract lifecycle: business term reviews, negotiation support, cross‑functional approvals, and version control.
  • Serve as a point of contact for contract‑related queries across Clinical/Legal/Finance.
• Financial Coordination & Execution
  • Validate vendor invoices and supporting documents against contract terms and milestone evidence.
  • Coordinate with study teams to confirm service completion and ensure timely internal payment processing.
  • Track committed costs and CO impacts; support ongoing study budget monitoring.

• Documentation & Cross‑functional Coordination
  • Maintain audit‑ready archives (electronic & physical) for procurement, contracts, and vendor performance records.
  • Prepare first‑draft contracts using standard templates; coordinate efficient cross‑functional reviews and approvals.

Qualifications:

• Bachelor’s degree or above in Life Sciences, Pharmacy, Biology, Public Health, Business Administration, or related fields.
• 6–12 years in pharma/biotech/CRO; ≥2 years hands‑on in vendor management / contracts & budget / CO handling.
• Exposure to outsourced study models and clinical project execution.
• Solid understanding of GCP, local regulations, clinical outsourcing models, and the clinical tech vendor landscape.
• Project coordination, cross‑functional communication, cost & risk analysis, process design/optimization, and documentation rigor.
• Excellent communication skills in both Mandarin and English (written and spoken)
• Experience in metabolic diseases (Obesity, T2DM, MASH), infectious disease, or other chronic high-priority therapeutic areas preferred