Job Title: Senior Scientist/Principal Scientist, in vitro Biology

Reports To: Director of Biology

Location: Shanghai, China

About Us:

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Position Summary:

Structure Therapeutics is seeking experienced scientist with strong biophysics experience in Shanghai. This role supports in vitro pharmacology and biophysics efforts to advance our internal drug discovery programs, with a primary focus on GPCR targets. Responsibilities include assay development, CRO management, and cross-functional collaboration, all contributing to our mission of making medicine more accessible.

Job Responsibilities:

• Develop and optimize binding and functional assays.
• Manage and coordinate CROs to deliver reliable, well-documented results.
• Generate high-quality data on binding or function kinetics and affinity.
• Scout and integrate new technologies, vendors, and advisors into the platform.
• Present data in project team discussions and represent the function.
• Collaborate in a matrixed team to support discovery pipelines.

Qualifications:

• D. in pharmacology, biochemistry, biophysics, or related field (or M.S. with significant experience).
• Hands-on expertise in biochemical/biophysical assays (e.g. TR-FRET, FP, RLA).
• Experience managing CROs and ensuring data quality.
• Strong communication skills and team-oriented mindset.

Travel Required: No

Structure Therapeutics Inc. is an Equal-Opportunity Employer.

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.

At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, ongoing performance-based equity and various benefits offerings.

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees.

We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.

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