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Sr. Associate, Analytical Development

Semma Therapeutics

Semma Therapeutics

Boston, MA, USA
Posted on Wednesday, July 10, 2024

Job Description

Position Overview

Vertex is seeking a talented scientist to join our Analytical Development group in Boston, MA. As a member of an industry leading CMC team, this individual will help advance transformative medicines treating the underlying cause of serious diseases by contributing to analytical chemistry activities for small molecule development programs from preclinical through to late-stage development. Responsibilities include analytical support of process and formulation development activities, purity and stability characterization of drug substance and drug product, as well as contributing scientifically to the resolution of broader drug development challenges in collaboration with other R&D functions. The ideal candidate will have knowledge of laboratory techniques commonly used in the analysis of pharmaceuticals such as HPLC, GC, and KF.


  • Designs, conducts, and interprets experiments following established methodology, procedures, and SOPs with the assistance of manager when necessary
  • Collates and interprets data systematically, and compiles results into conclusions or recommendations for discussions with manager
  • Demonstrates ability to handle multiple activities for a study
  • Performs basic experimental troubleshooting
  • Maintains accurate laboratory notebooks with inclusion of or references to sources of raw data
  • Responsible for assigned project work, may serve as project team representative
  • Authors reports, as assigned
  • Participates in the preparation of presentations and may present experimental conclusions at internal department or project team meetings
  • Performs other duties as assigned


  • Strong, documented academic performance in Chemistry
  • The ability to work successfully in a team/matrix environment
  • The ability to work in a fast-paced environment, manage priorities, and maintain timelines for multiple projects
  • Understanding of HPLC, KF, GC, and other techniques commonly used for pharmaceutical analysis
  • Demonstrates understanding of own discipline and aspects of drug development regulations and compliance
  • Demonstrates ability to provide high quality data collected in a compliant fashion in support of regulatory submissions and/or manufacturing
  • Demonstrates effective, self-sufficient communication skills, especially in peer/team discussions
  • Demonstrates awareness of other development disciplines
  • Problem solving and troubleshooting abilities
  • Good written and verbal communication skills

Education and Experience:

  • Bachelor’s or master’s degree in chemistry, Chemical Engineering, Pharmaceutical Chemistry or other natural science

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at