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Director, Global Commercialization, Heme

Semma Therapeutics

Semma Therapeutics

Boston, MA, USA
Posted on Friday, May 3, 2024

Job Description

Director, Global Commercialization - Heme

Location: Boston, MA (3 days onsite, 2 days remote weekly)

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) and Sickle Cell Disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, hemoglobinopathies, APOL-1 Mediated Kidney Disease, Duchenne Muscular Dystrophy, Alpha-1 Antitrypsin Deficiency, and pain.

General Summary:

In this key strategic role, the Director will be a critical leader within the Heme Global Commercial team supporting CASGEVY (exagamglogene autotemcel, or ‘exa-cel’). They will be accountable for driving the full Global potential of this first-of-its-kind innovation across both indications. The role will have a strong focus on commercialization strategy of CASGEVY. The successful candidate is highly strategic, thrives in an environment of uncertainty and rapid change, demonstrate cross-functional leadership and has a problem-solving mindset with analytical skills. This role is an individual contributor and reports to the Sr Director, Global Commercialization.

Key Duties and Responsibilities:

  • Co-Lead and successfully develop CASGEVY LCM commercial strategy, ensuring alignment with organizational objectives

  • Spearhead special strategic projects with VP/DAE in line with business priorities

  • Partner with International and across functions on innovative ways aimed at reaching our global patients, focusing on expansion opportunities

  • Lead, develop and champion disease strategy documents, including Brand Plan

  • Partner with Competitive Intelligence to articulate the Heme portfolio positioning and inform response & reaction to market events

  • Partner with Market Research to bring the voices of our patients into our strategic thinking

  • Support the global commercial team by providing clear direction for the Heme portfolio as the primary forum for commercial collaboration and alignment

  • Evaluates ROI for activities of the brand

  • Manage Heme global commercial governance body’s agenda and priorities to drive senior management endorsement

Qualifications - Education & Experience:

  • Bachelor’s degree required

  • Advanced degree in business or scientific discipline is preferred

  • Typically requires 10 years of experience or the equivalent combination of education and experience

  • Experience with International markets and diverse commercialization models

  • Consulting background preferred: ability to autonomously drive strategic projects, including framing complex challenges, opportunity assessments, and senior leader communication

  • Analytical mindset, with demonstrated ability to lead others to solve complex problems

  • Demonstrated ability to develop brand strategy, assess trade-offs, and monitor performance

  • Advanced therapeutic modalities a plus

  • Experience in pharmaceutical industry or closely related field(s) (e.g. healthcare consulting, etc.)

  • A solid compliance mindset, demonstrated integrity on the job, embrace of the Vertex values


Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at