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Commercial Technology Portfolio Manager

Semma Therapeutics

Semma Therapeutics

Boston, MA, USA
Posted on Saturday, March 9, 2024

Job Description

General Summary

Vertex’s Data, Technology and Engineering (DTE) team is seeking a Director, Commercial Technology Portfolio Management to join our Project Management and Strategic Operations group. Project Management and Strategic Operations is charged with streamlining and simplifying the work of our data and technology teams and ensuring the successful deployment of new technologies across our global enterprise. The Director, Commercial Technology Portfolio Management will report to our Head of Project Management and Strategic Operations and partner directly with our Head of Commercial Technology to oversee the full Commercial Technology portfolio of new technology implementations to enable small molecule and cell and gene therapy commercialization. This role would also include management of our Pain Launch Technology Program designed to deploy the technology capabilities that enable global launch of our pain medicines. The role requires portfolio planning, financial management, governance, and oversight of project and change management. The successful candidate will demonstrate a deep understanding of pharmaceutical commercialization disciplines, a strong background in program and portfolio management, and expertise in the deployment of enterprise technologies for commercial functions.

Responsibilities include:

  • Management of the Commercial Technology new implementation portfolio
    • Maintaining technology roadmaps, ensuring alignment with strategic priorities, and resource and capacity management
    • Developing and managing governance processes for technology implementations to ensure tight coupling to business requirements, executive sponsorship, and strategic priorities
    • Co-developing communication decks for regular portfolio reviews and presentations to executive leadership
    • Co-facilitating technology strategy and portfolio review meetings with senior leaders
    • Influencing cross-functional stakeholders to ensure strategic thinking, sound decision-making, and proactive risk/issue mitigation across the portfolio
    • Managing, coaching, and training all project managers for Commercial Technology implementations to ensure excellence in project delivery
    • Communicating portfolio status to Head of Project Management and Strategic Operations and DTE leadership to ensure cross-functional awareness and alignment
    • Managing the portfolio budget including accruals and forecasting
  • Leadership of the Pain Launch Technology Program including:
    • Developing and maintaining a comprehensive program plan including goals, objectives, timelines, budget, and resourcing
    • Driving the program forward to deliver those goals with excellence, on time and within budget
    • Identifying risks and issues and developing mitigation plans to ensure the success of the program
    • Managing stakeholders across commercial and technology subgroups and among vendors to ensure strong collaboration, communication and alignment
    • Monitoring program progress, reporting on milestones and deliverables to key stakeholders
    • Collaborating with program executive sponsors across commercial, finance, manufacturing and supply chain, and other functions to ensure strong communication and alignment with strategic vision


  • Advanced degree in business or scientific discipline or Bachelors degree in computer science with strong experience in biotechnology in an industry setting
  • 10 years of experience or the equivalent combination of education and experience
  • A minimum of 3 years of experience in program and portfolio management and exceptional organization and planning skills
  • Experience in management of commercial technology deployment, particularly commercial data warehousing, marketing automation, content management, and CRM
  • Proven track record of successfully managing complex projects, coordinating cross-functional teams, and delivering results within defined timelines and budgets
  • Exceptional communication and presentation skills, with the ability to effectively communicate complex commercial and technological concepts to both technical and non-technical audiences
  • Strong leadership skills with the ability to influence and collaborate with stakeholders cross-functionally and at all levels of the organization
  • Clear and succinct written and verbal communication is strongly preferred

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at