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Process Chemistry Scientist, 12 month FTC

Semma Therapeutics

Semma Therapeutics

Oxford, UK
Posted on Thursday, February 1, 2024

Job Description

General Summary:

The Process Chemistry Scientist will design and perform synthetic organic experiments efficiently, with a high degree of independence, and appropriately to the stage of development (pre-clinical through Phase 3). The post holder will outline study designs and execute on complex experiments.

Key Duties and Responsibilities:

  • Work as part of a team creating and improving synthetic approaches to pharmaceuticals
  • Plan and execute synthesis at gram to kilogram scales
  • Develop process understanding through the collection and analysis of data
  • Innovate as a member of the team to solve problems and address project needs
  • Support the team’s delivery of drug substance and intermediates through both in-house synthesis and the use of outsourcing
  • Communicate effectively within an extended team across functional boundaries
  • Makes conceptual contributions to development activities and scientific strategies; introduces some new methodologies and solutions to overcome synthetic and manufacturing obstacles.

Knowledge and Skills:

  • Thorough grounding in the core elements of synthetic Organic Chemistry
  • Demonstrable track record of solving complex synthetic problems through own achievements in the laboratory, in either an academic or industrial setting
  • Skilled in the purification and analysis of organic compounds (NMR, HPLC and mass spectrometry)
  • Excellent verbal and written communication skills to explain complex technical/scientific information to others in a straightforward manner
  • Knowledge of scale-up chemistry and Process Development a plus, but training can be provided to a talented Chemist.

Education and Experience:

  • PhD in Organic Chemistry or BSc/MSc in Chemistry plus experience equivalent to a PhD.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at