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Senior Manager Equipment Engineer

Semma Therapeutics

Semma Therapeutics

Boston, MA, USA
Posted on Friday, September 22, 2023

Job Description


The Manager, Instrumentation Engineer will be responsible for assessing non-GxP facility feasibility for new or moving lab-based equipment. This role will mitigate business risk by ensuring equipment has been assessed to align with facility’s capacity – including but not limited to electrical, mechanical, structural and utility assessments - prior to procurement. Role also considers holistic impact assessment of procuring multiple pieces of equipment for the lab or related spaces. This role will work closely with Facilities, Lab Instrumentation, Space Planning, Engineering and PMO teams as well and end users within R&D.


  • Complete facility assessment for equipment at time of CapEx budget approval and/or procurement execution.

  • Support technical assessment needed ahead of building shutdowns.

  • Support technical assessment related to lab equipment failures, as needed.

  • Providing support on new/existing/relocation requests as needed, including support of these projects managed by the PMO team.

  • Supporting R&D end users with equipment that requires design conversations/considerations (i.e. not off-the-shelf).

  • Provide and promote high standards of professionalism, integrity, and leadership, both within and outside the organization, appropriately representing Vertex core values, business philosophies, protocols, and standards.

  • Cultivate change and innovation by seeking opportunities to strengthen and improve existing services and operations.


  • Mechanical, Electrical, Plumbing (MEP) engineering expertise.

  • Ability to read P&ID drawings for building systems and can properly execute walkdown of lab and facility areas.

  • Eagerness to understand instrument design beyond his/her subject matter expertise.

  • The candidate must be able to build and maintain strong, cross-functional relationships with key stakeholders and be a trusted team leader.

  • Ability to work at a fast pace on multiple projects of a critical nature.

  • Strong understanding of operations principles and practices.

  • Ability to assess issues with a high degree of critical thinking, sound judgment, and the ability to adapt to changes in priorities or the work environment.

  • Ability to take qualitative equipment requirements and convert to technical specification line items.


  • Bachelor’s degree (or equivalent) required. Mechanical, electrical, or chemical engineering degree preferred.

  • 6+ years of experience in biotech/pharmaceutical laboratory environment

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at