Spring 2026 Co-op: Quality Control
Prime Medicine
Company Overview:
Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.
Prime Medicine is currently progressing a diversified portfolio of investigational therapeutic programs organized around our core areas of focus: hematology, immunology & oncology, liver and lung. Across each core area, Prime Medicine is focused initially on a set of high value programs, each targeting a disease with well-understood biology and a clearly defined clinical development and regulatory path, and each expected to provide the foundation for expansion into additional opportunities. For more information, please visit www.primemedicine.com.
Co-op Assignment Overview
Prime Medicine is seeking a co-op for the Spring 2026 semester with experience in biological or chemical techniques to join the Analytical Development and QC team. The candidate will learn cutting-edge technology in the field of gene and cell therapy, obtain hands-on experience with a broad range of analytical techniques, gain understanding in the scientific and regulatory requirements for phase appropriate analytical testing, and play a key role in solving complex technical challenges related to our prime editing strategy. This is a unique position with the opportunity to contribute directly to the advancement of prime editing programs toward the clinic.
We want curious problem solvers who enjoy working on exciting projects, working within a team, and are passionate about developing genetic editing technologies to better human health and well-being.
Primary Responsibilities:
- Support product development sample analyses, in-process, release and stability testing for:
- LNP-based drug products
- Prime editing component RNAs
- Participate in stability and reference standard programs, including protocol/report preparation, data compilation, and trend analysis, etc.
- Assist with sample management
- Conduct clean room lab environmental monitoring for GMP manufacturing suites
- Document and communicate experimental data in electronic notebooks per cGMP requirements
- Collaborate with teammates across the organization and program teams to support the product and method development, method qualification.
- Contribute to laboratory functionality, safety, and QC process optimization
- Flexibility to support taking on new projects and troubleshooting as needs arise and priorities are dynamic
- Identify opportunities for assay optimization, process improvements, and automation
Qualifications:
- Currently enrolled in B.S./M.S. program in Biology, Biochemistry, Biotechnology, Bioengineering, Microbiology, Chemistry, Chemical Engineering, pharmacology, or a related field
- Completion of foundational biology, biochemistry, microbiology, or chemistry coursework with a laboratory component
- Ability to work both independently and collaboratively
- Flexibility in taking on new projects and troubleshooting as needs arise
- Self-motivated, detail-oriented with strong attention to problem-solving ability, and organizational skills
- Excellent verbal and written communication skills
- Eagerness to learn GLP/GMP practices and new analytical techniques
- Comfortable engaging in cross-functional teamwork and communication
- Ability to handle multiple projects in a fast-paced environment.
Preferred Qualifications:
- Understanding of fundamental principles behind biological, microbiology, or chemical techniques, such as UV-vis, HPLC, UPLC, LC-MS, PCR/qPCR/ddPCR, potency assay, CFU identification and counting, etc.
- Hand-on experience with biological or chemical analytical techniques, such as sample extraction, preparation, dilution, and analysis are preferred
- Knowledge and/or experience in the field of gene and cell therapy, or willingness to learn
- Previous intern or co-op experience in biotechnology industry
What We Offer:
- A cutting-edge team open to mentorship and networking.
- Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
- Participation in regular seminars with industry experts.
- Full participation in employee activities including learning and development offerings, social activities, etc.
NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.
Prime Medicine is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law.