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Position Overview:

We are seeking an Associate / Sr. Associate Scientist who is technically skilled, self-motivated, and organized to join our multidisciplinary program team focused on developing novel engineered prime editing therapies targeting vision loss. This desired candidate is expected to have strong experience in cell and molecular biology, and assay development skills. Primary responsibilities will include but are not limited to mammalian cell culture, molecular cloning, delivering gene editing reagents into suspension/adherent cells, assay development (qRT-PCR, ddPCR), cell line development, in vitro functional assays, and assessing gene editing frequency by NGS. The candidate will have the opportunity to work with talented, highly collaborative cross-functional teams engaged in developing next generation gene editing therapies for patients.

Primary Responsibilities:

• Perform a variety of research activities requiring molecular biology and cell biology skills including PCR, qPCR, and DNA and RNA isolation
• Contribute to the scientific discussions and output of the team
• Assist in the design and assembly of molecular reagents and maintenance of cell culture
• Assist in the development of assays for the Ocular Targets Team
• Conduct experiments, collect and analyze experimental data, compile experimental summaries in an Electronic Lab Notebook (ELN), and present results to the larger team
• Document, present, and communicate scientific findings
• Adhere to all laboratory safety requirements and procedures

Qualifications:

• A BS or MS in Biology or related discipline with ideally 2+ years of experience with molecular biology, biochemistry, or related fields
• Effective communication skills, with the ability to describe research clearly and concisely to a cross-disciplinary audience
• Proficiency in molecular biology skills, including PCR, qPCR, and DNA and RNA isolation
• Experience in maintaining mammalian cell cultures and performing transfections
• Experience with next-generation sequencing sample preparation and data analysis
• Familiarity with gene and protein engineering, gene therapy, synthetic biology, or biotechnology is a plus
• Experience conducting experiments, collecting, and analyzing experimental data, compiling experimental summaries in an Electronic Lab Notebook (ELN), and presenting results to the larger team
• Goal-driven, with strong organizational skills, including record keeping, documentation, and reporting of research
• Highly adaptable and comfortable in an environment with dynamic priority demands
• Ability to independently learn, understand, and utilize current and developing industry practices, techniques, and standards in a rapidly advancing field
• Self-motivated and effective at managing multiple projects in parallel
• Rigorous and conscientious, exhibiting care and thoroughness in data interpretation