Scientist - Analytical Development
Orchard Therapeutics
Fixed Term Contract 15 months (Maternity Cover)
Location: London, UK
Reporting to: Director, Advanced Analytics
Job Summary:
As a key member of the Global Analytical Development Team, this lab-based role will be responsible for supporting analytical testing related to process development activities at Orchard. This will include experiment design, acceptance criteria setting, experiment execution and data analysis of a range of analytical methods. This is an exciting opportunity for a well-qualified candidate to join an international company focused on transforming the lives of patients with rare disorders through innovative gene therapies. The position is available for a fixed term of 15 months.
Key Elements and Responsibilities
- Development and qualification of analytical methods applicable for cell and gene therapy programs.
- Maintenance and completion of accurate lab-based records and final reports to support internal analytical assay development activities as required.
- Performing and developing analytical methods including protein and cell-based tools, immunoassays and ddPCR.
- Assessment of novel equipment and methodologies.
- Tissue culture of primary cells, cell lines, as well as cell bank generation and appropriate record maintenance.
- SOP-writing to support activities as required including tech transfer to internal departments or external partners.
- Presentation of method development plans and results to the wider department and functional teams as requested.
- Support development and qualification of analytical methods at CMOs and CTOs as required. This may include performing data, final report and SOP reviews.
- Other activities as may be assigned.