Associate Scientist, Discovery Research
Compass Therapeutics
Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. Compass’ scientific focus is on the relationship between angiogenesis, the immune system and tumor growth. Our pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. These include modulation of the microvasculature via angiogenesis-targeted agents, induction of a potent immune response via activators on effector cells in the tumor microenvironment, and alleviation of immunosuppressive mechanisms used by tumors to evade immune surveillance. We plan to advance our product candidates through clinical development as both standalone therapies and in combination with proprietary pipeline antibodies based on supportive clinical and nonclinical data. We were founded in 2014 and are headquartered in Boston, Massachusetts. For more information, visit www.compasstherapeutics.com.
Our Discovery team is seeking a highly motivated, hands-on Associate Scientist II. The ideal candidate will have a proven track record of flow cytometry, cell culture, in vivo tumor mouse models, and desires to be part of a fast-paced and collaborative team. This position reports onsite to our Senior Scientist.
Responsibilities:
• Support the Compass Discovery teams’ efforts in identifying our next drug candidate within established timelines, from antibody characterization to in vivo tumor mouse models
• Perform characterization of antibodies and antibody variants through protein and cell binding experiments
• Plan and execute assay optimization and culture of cell lines, primary human cells and NHP cells
• Perform tissue culture and cellular assays using multicolor flow cytometry, ELISA, Western blot, PCR, RT-PCR
• Assess the therapeutic potential of candidate drug molecules using in vivo tumor mouse models
• Collect, analyze, and interpret data and troubleshoot experiments
• Maintain and implement good laboratory practices, including accurate and detailed electronic lab notebook (ELN), instrument and reagent validation, and write/update Standard Operation Procedures (SOPs)
• Support the maintenance of cell lines and primary cells inventories
• Collaborate with R&D team members to support research activities and company goals
• Present Discovery team progress and results; communicate effectively internally across functions and externally at conferences
Qualifications:
• Bachelor's or an Advanced degree in immunology, cell biology, immuno-oncology, or similar field
• 2+ years of lab experience, with relevant scientific experience
• Demonstrated experience with multi-color flow cytometry is required
• Proficiency with plate and cell-based assay development (ELISA or MSD), cell culture (cell lines, primary human and non-human primate immune cells/tissues) is preferred
• Prior experience with in vivo mouse tumor models highly desired
• Proficiency in Excel, GraphPad, FlowJo, PowerPoint and other Microsoft Suite Products
• Self-motivated, passionate about science, meticulous, flexible and eager to take on new tasks
• Strong ability to troubleshoot in a collaborative team‐oriented environment
• Strong interpersonal, analytical, organizational, and creative problem-solving skills
• Excellent task management, written and verbal business communication skills
• A strong desire to positively impact the lives of patients
At Compass, we provide employees with an inclusive offering of benefits and a competitive compensation package. We offer our employees competitive salaries, discretionary bonuses, and meaningful equity participation. Our innovative benefits support the health and wellness of our employees; from medical, dental and vision benefits to health reimbursement arrangement, flexible spending accounts, sponsored gym membership, an employee assistance program, life insurance, and much more. We also provide 401(k) and Roth 401(k) programs with a 6% company match, and other resources for financial wellness. Additional benefits include commuter reimbursement, subsidized company parking, cell phone reimbursement, Summer Fridays, and substantial paid time off including a winter shut down week.
Our Mission at Compass is to develop next generation antibodies into transformative cancer therapies that improve patients’ lives. Our Compass Core Values guide us in achieving this. We are mission-focused and share a passion for science and creativity that help us innovate in all that we do. Our unique community promotes authenticity, diversity of thought, and collaborative teamwork.
We invest in the growth and development of our teams and individuals through programs such as company-wide trainings, cross-functional collaboration and job shadowing, tuition reimbursement, employee recognition awards, and a comprehensive performance management cycle. Also, our Compass Culture Committee empowers employee-organized events that celebrate wins, drive initiatives, support local philanthropy, and align with our mission and values.