Companies you'll love to work for

LNP Science Co-Op

Beam Therapeutics

Beam Therapeutics

Cambridge, MA, USA
Posted on Oct 1, 2024

Company Overview:

Beam Therapeutics is committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Position Overview:

Beam is seeking a highly motivated co-op student to join our Lipid Nanoparticle (LNP) Science team from January through June 2025. The individual will work on advancing our screening platform to discover novel LNP compositions and optimize processes for high-throughput applications. They will be responsible for formulating, characterizing, and analyzing results. We are looking for an enthusiastic learner who enjoys problem solving and collaborative projects.

Responsibilities:

  • Formulate and characterize LNPs to determine size, polydispersity, concentration, encapsulation, and pKa using established assays and techniques
  • Participate in platform assay development, including testing of new materials and protocols
  • Evaluate the delivery of base editor technologies through in vitro and in vivo base editing studies
  • Document, summarize and present studies and findings to internal audience at group meetings
  • Document and manage all experimental planning and results in electronic lab notebook, including statistical analysis and troubleshooting where appropriate.
  • Adhere to all laboratory safety requirements and procedures, assist in maintaining general laboratory functionality, including maintenance of lab equipment and receiving of lab supplies

Qualifications:

  • Pursuing a BS or MS in biology, biochemistry, biomedical engineering, or related field of study with at least 1 year of relevant laboratory experience.
  • Must be a team player, comfortable working collaboratively and thriving in a fast-paced environment
  • Proficient in Excel, PowerPoint, and data analysis. Knowledge of GraphPad Prism or JMP.
  • Experience maintaining a lab notebook and following written protocols.
  • Motivated to learn and detail oriented with excellent organizational and communication skills.