mRNA Process Development Intern
Beam is looking for a highly motivated intern to join our RNA Process Development Team from June to August of 2024. The intern will assist in development and optimization of mRNA manufacturing processes. Specifically, this role will involve performing and optimizing in vitro transcription (IVT) reactions and running biochemical assays and chromatographic analysis to characterize the mRNA products. The ideal candidate for this role is detail-oriented, persistent, and has an innovative mindset toward solving technical challenges. This position will play a central role in advancing our core mRNA technology, while providing the individual exposure to one of the most important classes of medication of the 21st century.
- Perform transcription reaction optimization experiments; assist with screening of alternative IVT templates, enzymes, and nucleotides.
- Thoroughly analyze the product by capillary electrophoresis, gel electrophoresis, and high-performance liquid-chromatography.
- Work collaboratively with other teams to perform editing experiments in cells.
- Maintain detailed documentation of experiments in the ELN system.
- Adhere to all laboratory safety requirements and procedures.
- Pursuing a BS or MS in biological sciences or a related field (Bioengineering, Biochemistry/Biophysics, Cell Biology/Molecular Biology, Chemical Engineering) with at least 1 year of relevant laboratory experience.
- Knowledge of biochemical & molecular biology methods used in drug discovery and development.
- Proficient in Excel, PowerPoint, and data analysis.
- Experience maintaining a lab notebook and following written protocols.
- Motivated to learn and detail oriented with excellent organizational and communication skills.