Nuclear Metrology Expert
ARTBIO
Oslo, Norway
Posted on Dec 5, 2025
Summary
The Nuclear Metrology Expert will be responsible for the technical design, management, and execution of accurate plans for Th228 and its progenies, particularly Pb212 measurement, for targeted dose administration to the patient. The Expert will oversee our decentralized external manufacturing network and our internal R&D labs to support clinical trials and readiness for commercial deployment. The successful candidate will be an expert thinker with technical proficiency in nuclear physics and radiopharmaceutical development who will build a strong technical foundation around our strategic pillars, focused on our Pb212 candidate platform. In addition, the Nuclear Metrology Expert must have a profound understanding of the competitive landscape and the ability to integrate learnings and failures from others to improve the measurement standards obligation.
Main Duties and Responsibilities
- Responsible for sourcing, qualifying, validating, maintaining, and contracting necessary equipment to measure patient doses and impurities coming from our internal process through the entire TechOps value chain.
- Evaluate various options and possibilities of measurement of Th228 and Pb212 and progenies.
- Develop an operational plan for managing the calibration of equipment against international standards to transfer and manage an efficient manufacturing process of Th/Pb generator to our source holder CMOs, including the identification and implementation of appropriate manufacturing processes, equipment, use, and maintenance.
- Increase internal technical and operational capabilities to develop the platform, including continuous monitoring, improvement, and troubleshooting of our radioactive measurement (Th generator yield, radiochemistry form to label any Pb212-candidate of the platform, in process control, including QC and release time for both Th and Pb).
- Build the validation needed to deliver robust evidence to fulfill the ASMF and IND requirements, respectively, for the generator and the Drug candidate and the life cycle management of the dossier.
- Set up training, troubleshooting, and iteration improvement to nuclear physics education and participate in the internal and external awareness of our platform.
- Develop and maintain relationships with key suppliers and service providers to ensure the reliable and efficient supply of raw materials, equipment, and services.
- Ensure compliance with all relevant regulations, standards, and guidelines, including those relating to quality, safety, and environmental impact for our CMOs, internal R&D, and own projects for the use of Th and Pb.
- Identify and implement process improvements to increase efficiency, reduce costs, and enhance the safety and quality of the products and services provided by ARTBIO.
- Support the approval of the company’s manufacturing sites and their compliance with GMP, HSE, and QA standards.
- Communicate effectively with all stakeholders, including senior management, customers, suppliers, and regulators, to ensure cross-functional alignment on the strategic vision and objectives of the company.
- Stay abreast of technological advancements and market trends in the field of Th upstream processes and daughters’ mechanism and provide guidance to the senior management team on how ARTBIO can leverage these trends to enhance its competitive position.
- Provide technical leadership and guidance to the team on nuclear physics, materials science, and state-of-the-art radiopharmaceutical development.
Qualifications & Experience Required
- PhD in Nuclear Physics.
- Minimum of 5 years of experience in the nuclear development field, with a focus on manufacturing and process development of isotopes.
- Experience in manufacturing processes for radioactive materials.
- Demonstrated experience in developing and operating complex radioactive separation and control technologies, ideally in the field of Isotopes manufacturing.
- Experience from managing a team of engineers and nuclear scientists, with a track record of delivering projects on time, within budget, and to the required safety and quality standards.
- Strong technical knowledge and problem-solving skills in nuclear physics, materials science, isotopes separation techniques, Irradiation process, radioprotection, and radioactive accuracy measurement with the ability to think strategically and communicate effectively with all stakeholders.
- Excellent organizational and project management skills, with the ability to prioritize and multitask effectively.
- Familiarity with relevant regulations (FDA, EMA), radioactive standards reference (NIST), and guidelines, including those relating to quality, safety, and environmental impact.
- Familiarity with current US and EU regulatory requirements for therapeutic products.
- Written and verbal fluency in English.
About Us
ARTBIO is a clinical-stage radiopharmaceutical company redefining cancer care by creating a new class of alpha radioligand therapies (ARTs). The unique ARTBIO approach selects the optimal alpha-precursor isotope (212Pb) and tumor-specific targets to create therapeutics with the potential for highest efficacy and safety. The company's AlphaDirect™ technology, a first-of-its-kind 212Pb isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. ARTBIO is advancing multiple pipeline programs with lead program AB001 currently in first in human trials. ARTBIO is shaped by a long-standing scientific legacy with nearly a century of pioneering work in radiation therapy conducted at the University of Oslo and Norway’s Radium Hospital. For more information, visit www.artbio.com, and follow us on LinkedIn and Twitter.
As an emerging, global biotech with locations in Boston, Massachusetts, Basel, Switzerland, London, England and Oslo, Norway, we take advantage of diverse scientific depth and insights which makes ARTBIO a unique place to work. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration.
EEO Statement
ARTBIO is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
ARTBIO does not accept unsolicited resumes from external agencies or recruiters. Submission of a resume without a prior written agreement does not create any express or implied contract between ARTBIO and the agency. ARTBIO will not pay any fees related to unsolicited resumes.