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Senior Automation Engineer

Aera Therapeutics

Aera Therapeutics

Software Engineering
Cambridge, MA, USA
Posted on Oct 11, 2025

Senior Automation Engineer

Cambridge, MA

ABOUT US

Aera Therapeutics was founded by a world-class team of scientists, investors, and company builders with a shared vision to unlock the potential of genetic medicines across a broad range of modalities and therapeutic areas. We strive for excellence and an industry-leading position in our chosen delivery platforms, while aggressively hunting for opportunities where enabling delivery technologies can unlock applications of high, unmet medical need.

Aera has multiple proprietary delivery platforms including – targeted lipid nanoparticles (tLNPs), antibody oligonucleotide conjugates (AOCs) and protein nanoparticles (PNPs), – that are being developed to enable next-generation genetic medicines across a range of therapeutic modalities and disease areas. These platforms have the potential to overcome the limitations of today’s delivery technologies and expand the application of genetic medicines.

How will your role make an impact at Aera Therapeutics? We are looking for a Sr. Automation Engineer to join our Laboratory Technologies team here at Area. In this role, you will be responsible for the design and optimization of high-throughput workflows by automating lab processes, integrating informatics tools, and collaborating with scientists and vendors to improve efficiency, data quality, and scalability across scientific teams. You will be reporting to the Director, RNA Technologies and be expected to work onsite five days per week.

You will:

  • Design and implement high-throughput automated workflows to support protein and nucleic acid production, nanoparticle formulation, diverse purification solutions and analytical assays.
  • Partner with scientists and cross-functional teams to adapt bench protocols, develop screening strategies, and assess product function, stability, and solubility at scale.
  • Identify and resolve workflow bottlenecks to improve throughput and data quality across automated systems.
  • Integrate laboratory software and informatics tools for data acquisition, analysis, and visualization.
  • Create documentation, train end users, and provide ongoing support for automation systems and workflows.
  • Collaborate with external vendors to evaluate and deploy new automation technologies that advance Aera’s lab infrastructure.
  • Troubleshoot and support automation deployments at Aera

Qualifications:

  • Bachelor’s degree in science, engineering, or computer science with 8+ years’ of relevant experience or Master’s degree with 6+ years’ experience
  • Hands on experience with a variety of liquid handlers (i.e. Hamilton, Tecan, Biomek, Lynx)
  • Experience with laboratory automation integration and dynamic schedulers (i.e. GBG, Cellario)
  • Programming experience in a relevant or related language (python, C#, SQL preferred)
  • Experience with modern software practices including git, APIs, and cloud infrastructure
  • Experience with connecting instrumentation to laboratory information managements systems (LIMS), particularly Benchling)
  • Experience designing experiments and interpreting data in at least one of following areas: microbiology, molecular biology, mammalian in vitro cell culture and analytical assay development.
  • Commitment to our Core Values: Respect, Integrity, Excellence, Impact

Benefits:

  • Healthcare
  • 401K
  • PTO
  • Commuting subsidy
  • Parental leave

Aera Therapeutics is committed to providing equal employment opportunities by recruiting, hiring, training and promoting applicants and employees without regard to race, color, religion, creed, national origin, sex, age, ancestry, sexual orientation, genetics, pregnancy, marital status, familial status, victim of domestic violence status, gender identity/expression, disability, handicap, military obligations, veteran status or any other category protected by federal, state or local laws.