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Health Economics & Outcomes Research Director - UK/Ireland (Hybrid)

Semma Therapeutics

Semma Therapeutics

This job is no longer accepting applications

See open jobs at Semma Therapeutics.
Paddington, London W2, UK
Posted on Thursday, January 11, 2024

Job Description

Vertex Pharmaceuticals

Director, Health Economics & Outcomes Research - UK/Ireland


Vertex is seeking a talented individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society.

As a member of the International Health Economics and Outcomes Research (HEOR) team based in London, your primary responsibility will be to develop and oversee launch execution, and training in the UK & Ireland across disease areas.

The role will involve heavy global interaction and will be reporting into the Sr. Director HEOR for the International region. The right candidate should have strong interpersonal skills and significant experience working with cross-functional teams in a heavily matrixed environment.

You will be tasked with leading the development of local HE materials to support Vertex’s assets value proposition in the UK & Ireland and will have a large focus of leading the adaptation of global economic models, HTA dossier development, RWE local study design in full alignment with global research and training local teams in HEOR topics across disease areas.

The right candidate will have extensive HEOR experience and a significant understanding of European Market Access. You will need to have an in depth understanding of international HEOR processes and HTA submissions.

Key Duties & responsibilities

Act as the UK&I HEOR lead in cross-functional and cross-regional teams in order to:

  • Prepare submissions adapt/develop country-specific economic models and present economic evidence to HTA organizations.
  • Work closely with International P&R to adapt the global value story (GVD), reimbursement support materials, payer objection handler, and other evidence-based materials that demonstrate product value in a manner that is meaningful to national and regional payers.
  • Support the development of International Market access plans and associated strategies through continued collaboration with International P&R and Regional Market access colleagues
  • Support local markets to shape evidence generation plans and execution in order to strengthen value demonstration during reimbursement processes
  • Provide training on Health Economics tools underpinning value proposition to local markets

Required Education Level

An advanced degree in one of the following areas: Health Economics, Public Health, Biostatistics, Medicine, or another analytic field.

Required Experience

  • Experience in the pharmaceutical industry, with extensive years of HEOR experience.
  • In-depth and current understanding of international HEOR/payer environment, including reimbursement decision-making and HTA processes.
  • Experience in adapting global economic/budget impact models and other support materials to meet HTA requirements in the UK & Ireland (NICE, SMC, AWMSG, NCPE)
  • Demonstrated experience with product launches

Required Knowledge/Skills

  • Excellent communication skills, strong oral/written presentation skills.
  • Ability to navigate and be successful in a fast-paced environment.
  • A desire to be part of a highly innovative company aimed at transforming the lives of people (and their families) with serious diseases.


Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at

This job is no longer accepting applications

See open jobs at Semma Therapeutics.