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Pathology Senior Research Associate

Semma Therapeutics

Semma Therapeutics

Boston, MA, USA
Posted on Saturday, September 2, 2023

Job Description

General Summary:

The Pathology Research Associate will perform routine and specialized histology techniques, wet lab work, data acquisition and compilation using state-of-the-art molecular pathology techniques. The incumbent will interface closely with other scientists, veterinary pathologists and histotechnologists in PSA as well as other cross-functional project teams to provide timely, high-quality data to support multiple projects across our drug development pipeline.

Key Duties and Responsibilities:

  • Conduct routine histology techniques including tissue processing, trimming of tissues of diverse origin, embedding, paraffin block microtomy and cryo-sectioning
  • Setup and perform routine pathology staining techniques including H&E and special stains
  • Perform novel molecular pathology assays including IHC, RNAscope, multiplexing using automated platforms (Ventana and Leica) and manual methods
  • Perform routine maintenance and monitoring of laboratory equipment, keep accurate laboratory records, and ensure proper archiving of pathology specimens
  • Perform digital image analyses, while generating quantitative data using a variety of Image analysis software (e.g. HALO, MATLAB) to support discovery pathology programs.
  • Work with board-certified anatomic pathologists to review, QC, and approve algorithms
  • Careful record keeping, follows good laboratory and GLP-like practices.

Knowledge and Skills:

  • Ability to multi-task, prioritize and provide timely, high-quality results on multiple projects simultaneously in a fast-paced environment
  • Excellent written and oral communication skills are required

Education and Experience:

  • Requires a Bachelors/Masters degree in Biological Sciences
  • 1 to 4+ yrs experience working in a research-based laboratory.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at